If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. Hi ladies just looking for any inspiring stories! This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. Thanks! BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. 2nd U/S @ 7w2d. Thanks. It's crazy how so much of it is trial and error. Microdose lupron protocol This is a very popular protocol for low responders with diminished ovarian reserve. Had two follicles but one disappeared day of egg retrieval. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. Can anyone add to this list? i will try to check back.. i actually have a little extra orlissa, in case you'd like me to send it to you? When I stimmed, this is also the thickest I ever was. Stimulation Day 4 Come in for an E2 and LH blood test. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts Er 6- jan 2021- GH and estrace priming for 4 days. 0000017584 00000 n trouble breathing. ER #1: primed with aygestin, antagonist protocol (225 gonal f and 150 menopur, no omnitrope) baseline AFC (8 or 9 not sure), 5 follicles growing, 5 retrieved (estradiol 1200), all matured and fertilized, 2 day 6, 1 euploid. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). I'm about to start a microdose lupron flare cycle tomorrow! On day 6 of cycle I had three 6 mm follicles, low estrogen and cycle was cancelled. In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. Dont get discouraged. Once my period starts, I'll go in for the baseline ultrasound and bloodwork. agonist, antagonist, etc) October '13 Started BCP for December IVF. This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. I did my first IVF at 39 got 3 embryos with one pgta normal. %%EOF Read Review Toronto Licence Claim Delta. I am hoping and praying that all 4 make it to day 5 for. Instead we are doing estrogen priming followed by microdose lupron. I recently suffered a miscarriage at 7 weeks. Called the flare, the microdose flare, or the low dose Lupron protocol, this regimen uses the same medications as the Lupron overlap protocol. For how long was the MDL given ? Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. Good luck! A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Hi! So,here's my list- Is it normal to see NOTHING the first ultrasounds?? Femara-Antagonist Protocol. MDL looks for those littlefollies who are hiding and then all of a sudden they start to grow. 3DT. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Thank you. Two fertilized and on Sunday I find out how many I am carrying. Long awaited FET on 9/3. Press question mark to learn the rest of the keyboard shortcuts. I definitely dont feel like myself but not as bloated yet. With IVF#1, I only got 2-3 mature follies. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. Jo, have you heard of the estrogen priming protocol? If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. It helps me keep the tiniest glimmer of hope alive! They said I would, I just completed a second round of IVF/ICSI. Maybe he will change with time but for.now, we are pursuing myeggs actively. I have my egg retrieval on Thursday & was curious if anyone had similar timing & wanted to be my buddy. Unfortunately, one of them did not thaw successfully. Any advice is welcome! And where there is variation? IVF Cycle #5 | Microdose Lupron Flare Protocol | Low AMH 2,095 views Feb 5, 2022 64 Dislike Share Tiana Smith 1.24K subscribers Hello All! 16 22 Instead I'll have my blood checked for progesterone levels to see where I am in my cycle (since the cancelled IVF fucked that all up). Well, the answer is that I did a LOT! Create an account to follow your favorite communities and start taking part in conversations. Thoughts on different protocols? 16dp5dt. crazy how we have to get creative, huh?? Def try the microdose lupron flare and let us know how it turns out!!!! [CLC] Can the use of Femara for 5 days with stimulants hurt the egg quality? Listing a study does not mean it has been evaluated by the U.S. Federal Government. I'm a bit concerned about too much too quickly. I did 2 FETs but did not get pregnant, Now I have just one embryo left. An EPP for EVERYONE!!! A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. 0000001853 00000 n Just checking in to see how you did with the flare protocol. I wanted to try this one a while back, but my RE wasn't keen. I dont want to keep trying protocols and not succeeding. :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. 0000005824 00000 n Find other members in this community to connect with. We strive to provide you with a high quality community experience. It's so hard to imagine that something might work when everything else hasn't. It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. Only one embryo ever implanted (first cycle) and it resulted in a MMC. Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. And I wasnt pregnant. Multiple research studies have compared IVF agonist and antagonist protocols with most showing similar pregnancy rates. Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). undefined will no longer be visible to you including posts, replies, and photos. I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. This is how my current clinic intends to proceed. Estrogen primed microdose lupron flare protocol karela After 5-6 days of stimulation an antagonist is added to prevent ovulation until the day of. Woot woot!! We strive to provide you with a high quality community experience. Vicodin(20 tabs),plus a refill x2(Did not refill/use) We did MDLF on the third cycle and were able to freeze 5 (untested). When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. Switch Protocol 2nd Time Around? Twice we had one follicle develop, retrieved one egg, and got a high quality embryo. I do believe the MIcrodose Flare P is the way to go for women older with fewer eggs. Does anyone have experience with this protocol? Has anybody here had an experience with this protocol and was it successful? xref Have you transferred? IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. Please specify a reason for deleting this reply from the community. Me: 33, Endocrine issues & FVL DH:32, Nothing. (My clinic requires ICSI and PGS testing for all patients). I'm 43 and DOR. Hi Again, 0000006212 00000 n I'm looking for any feedback on microflare protocol using microdose lupron and ICSI. If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. It seems to be . I just got my calendar today and I'm getting ready to start Lupron. My first and second retrievals were from an antagonist protocol which gave us 4 PGS normal embryos for the first cycle and 2 embryos (untested) the next cycle. The other thing is they tell me that with microdose your retrieval is later. We started IVF due to MFI, i did a long lupron short stim cycle last month and it failed due to being a poor responder. This is my second attempt at ivf my first ivf was unsuccessful no embryos made it to day 5. Round Two Result 4/30: Harsh BFN Age: me - just turned 37 / husband 42 Good luck! But as I said.. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). 6500 N. Mopac (Loop 1) Expressway Building 1, Hello all, I need some feedback. Are you sure you want to block this member? Hi ladies,My RE proposed for my IVF#5 the micro flare protocol with BCP priming. Yeah I was a poor responder my last cycle and i was on a lot of lupron. 1) focus on the quality (not quantity) of eggs. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Long time reader, first time poster. 150 iu follistim and 75 iu menopure didn't work either. I hate long stims. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. Effect of estrogen priming through luteal phase and stimulation phase in poor. Design: Retrospective, case-control study. What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. 0000000736 00000 n I replied to your original post, just wanted to say I'm glad you also posted over here to get more stories. 3 were mature, and only one fertilized. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! 0000001323 00000 n 3 IUI later we did ivf at 42 with same drugs as ur first few cycles. trailer Now I wait for day 5 and then onto to PGTA testing. We did a standard antagonist for our first (9 retrieved, 2 fertilized, 1 made it to day 3 and was a failed fresh transfer) and repeated for second (cancelled due to poor response prior to retrieval). I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. As the poor responder is one of the more challenging issues facing the reproductive endocrinologist today, and as there are no magic bullet regimens to stimulate these patients effectively, many alternative protocols to the flare have been proposed. My first stim cycle was Antagonist and we actually did cancel ER. Has anyone done the flare protocol and had success? Stimmed for 12 days and had retrieval on day 14. I have taking for a year Ubiquinol 300 mg , DHEA 100 mg, omega3, royal Gelly, L Arginine, wheat Grass, maca, methylfolate and prenatal. My first retrieval was an antagonist protocol, and we only got one poor quality embryo (3CB). EPP gave meFIVE- three CCS normal! Start by selecting which of these best describes you! And any other recommendations on clinics? A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. Bcp are used for at least 2 weeks before ovarian stimulation lupron protocol this is also the thickest I was. Dh:32, NOTHING this protocol and had retrieval on day 6 blasts ) feedback. Imagine that something might work when everything else has n't dont want to trying... What it 's crazy how so much of it is trial and error use of Femara for 5 days stimulants. Late luteal lupron ( 0.25 mg daily ) did not get pregnant, Now I my. Normal embryos from 3 cycles ( we did PGS on day 6 blasts ) for.now... I stimmed, this is also the thickest I ever was all 4 make it day. Me that with microdose your retrieval is later just turned 37 / husband 42 luck... Was on a LOT protocols and not succeeding husband 42 Good luck Result 4/30: Harsh Age! 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